The Reactions of Ethyl 2-Furanacrylate with Grignard Reagents.
نویسندگان
چکیده
منابع مشابه
Copper-catalyzed asymmetric allylic substitution with aryl and ethyl Grignard reagents.
Phenyl- and ethyl-magnesium bromides undergo regioselective asymmetric allylic substitution with high enantioselectivity under the catalysis of chiral amidophosphane-copper(I) complexes.
متن کاملStereospecific Nickel-Catalyzed Cross-Coupling Reactions of Benzylic Ethers with Isotopically-Labeled Grignard Reagents
In this manuscript we highlight the potential of stereospecific nickel-catalyzed cross-coupling reactions for applications in the pharmaceutical industry. Using an inexpensive and sustainable nickel catalyst, we report a gram-scale Kumada cross-coupling reaction. Reactions are highly stereospecific and proceed with inversion at the benzylic position. We also expand the scope of our reaction to ...
متن کاملDi-Grignard reagents and metallacycles
Aliphatic ,w-dibromides can be converted to the corresponding c,w-di—Grignard reagents; for those members carrying less than four carbon atoms between the functions, special procedures are required. The synthesis, structure and applications of the di-Grignard reagents are discussed; particular emphasis is placed on the structures of the corresponding cyclic dialkylmagnesiums, and on the use of ...
متن کاملIron-catalyzed desulfinylative C-C cross-coupling reactions of sulfonyl chlorides with grignard reagents.
Carbon–carbon cross-coupling reactions are very important in the areas of material science and medicinal chemistry. Most current methods require expensive transition-metal catalysts (for example, based on Cu, Pd, Co, Ni, Pt, Ru, and Rh) and ligands (for example, phosphines). Early reports by Kharasch and Reinmuth in 1954 and then by Tamura and Kochi in 1971 suggested that inexpensive Grignard r...
متن کاملThermal epimerization of diastereomeric Grignard reagents.
Thermal epimerization is the key to changing the endo-to-exo ratio of the diastereomeric bornyl and fenchyl Grignard reagents from 67:33 to 96:4 and from 20:80 to 80:20, respectively.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1977
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.31b-0719